Interactive Case Study Companion
i - Learning Objectives
ii - Resources
iii - Scenario
1 - Blood smear, initial presentation of chronic myeloid leukemia (CML) - Low power
2 - Blood smear, initial presentation of chronic myeloid leukemia (CML) - High power
3 - Philadelphia chromosome-positive CML - Initial karyotype
4 - Blood smear, blast phase of chronic myeloid leukemia (CML) - Low power
5 - Blood smear, blast phase of CML - High power
6 - CML, blast phase - Flow cytometric analysis
7 - CML, blast phase - Karyotype
8 - Restriction (enzyme) map of BCR and ABL loci, normal and rearranged - Schematic
9 - BCR in genomic DNA of CML - Southern blot analysis
10 - Exon structure of the BCR, ABL, and BCR/ABL genes - Schematic
11 - Amplified BCR/ABL fusion transcripts (mRNA-derived cDNA) - PCR products
12 - Restriction map of the IGH locus - Schematic
13 - JH in CML genomic DNA - Southern blot analysis