Interactive Case Study Companion

Wilms tumor
Uninvolved kidney
Wilms tumor, medium power

5 - Kidney, Wilms tumor (nephroblastoma) - Gross, cut surface  
The tumor involves both the upper and lower poles of the kidney. The tumor is well circumscribed and firm. Histologically, Wilms tumors may recapitulate different stages of nephrogenesis. They contain blastemal, stromal, and epithelial cells. The epithelial differentiation shown here forms rosettes or tubules.

Review: Pediatric Disease Case 3, Images 5-7 (Wilms tumor, gross and microscopic).

What genetic abnormalities and malformation syndromes are associated with Wilms tumor?
What is the survival rate for Wilms tumor?


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